Comprehensive Natural Products Chemistry : Enzymes, Enzyme Mechanisms, Proteins and Aspects of NO Chemistry

Comprehensive Natural Products Chemistry : Enzymes, Enzyme Mechanisms, Proteins and Aspects of NO Chemistry by -

Title: Comprehensive Natural Products Chemistry : Enzymes, Enzyme Mechanisms, Proteins and Aspects of NO Chemistry
Author: -
ISBN10: 0080431577
ISBN13: 978-0080431574
Publisher: Pergamon Pr (February 1, 1999)
Language: English
Subcategory: Chemistry
Size PDF: 1910 kb
Size Fb2: 1734 kb
Rating: 4.9/5
Votes: 403
Pages: 533 pages
Other Format: lrf mbr docx mobi

Comprehensive Natural Products Chemistry : Enzymes, Enzyme Mechanisms, Proteins and Aspects of NO Chemistry by -


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Hardbound. This volume describes the dramatic advances in studies of the structure and function of enzymes which have led to an understanding of the rich chemistry used by nature to construct molecules and how the enzymes of natural products biosynthesis catalyze these reactions. Natural products are synthesized from simple precursors through a series of enzyme mediated reactions that are exquisitely selective and efficient. Questions about the mechanisms of these reactions and what features of enzyme catalytic sites are important for stabilizing transition states and reactive intermediates have been addressed by combining studies in mechanistic organic chemistry, structural biology, and molecular genetics. Except in rare instances, the enzymes of natural products biosynthesis are not found in abundance, and as a consequence, they are not readily available for study from natural sources. This situation has changed through the dramatic advances in gen