Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical Practice by -Title: Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical Practice
Publisher: Springer; 2010 edition (October 29, 2009)
Subcategory: Medicine & Health Sciences
Size PDF: 1327 kb
Size Fb2: 1353 kb
Pages: 409 pages
Other Format: azw mbr lrf lit
Lung Cancer Metastasis: Novel Biological Mechanisms and Impact on Clinical Practice by -
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Lung cancer is the leading cause of cancer-related mortality. Metastatic lung cancer is responsible for more than ninety percent of lung cancer related deaths. However, relatively little progress has been made in understanding the process of lung cancer metastasis. The two main aims of this book are a) to introduce clinical aspects to basic scientists and basic molecular and cellular concepts to clinical investigators, in order to promote collaboration and foster much needed translational research; and b) to introduce new and emerging concepts and approaches in metastasis research to lung cancer research community at large.
In this attempt, the book will cover a broad spectrum of subjects ranging from the current trends in the clinical management of the metastatic disease, to the systems biology approach for gaining insights into the mechanisms of metastasis. Some of the subjects covered will include: defining basic hallmarks of a metastatic cell, the concept of tumor stem cells, epithelial-mesenchymal transitions, evasion of immune-surveillance, tumor-stromal interactions, angiogenesis, molecular imaging and biomarker discovery.