Drug Metabolism: Chemical and Enzymatic Aspects

Drug Metabolism: Chemical and Enzymatic Aspects by Jack P. Uetrecht, William Trager

Title: Drug Metabolism: Chemical and Enzymatic Aspects
Author: Jack P. Uetrecht, William Trager
ISBN10: 0849375959
ISBN13: 978-0849375958
Publisher: CRC Press; 1 edition (June 20, 2007)
Language: English
Subcategory: Medicine
Size PDF: 1619 kb
Size Fb2: 1869 kb
Rating: 4.4/5
Votes: 390
Pages: 192 pages
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Drug Metabolism: Chemical and Enzymatic Aspects by Jack P. Uetrecht, William Trager


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In order to understand drug metabolism at its most fundamental level, pharmaceutical scientists must be able to analyze drug compound structure and predict possible metabolic pathways in order to avoid the risk of adverse reactions that lead to the withdrawal of a drug from the market. This title is a comprehensive guide for recognizing the chemical underpinnings of drug metabolism. While there are numerous resources available to medicinal chemists for understanding drug structure, and to pharmacologists for discerning drug metabolism from a biological standpoint, no resource currently exists that links the chemical and biological aspects in language accessible to both-making it challenging for both groups to fully comprehend how a drug is metabolized, as well as the potential effects of the metabolites. Drug Metabolism: Chemical and Enzymatic Aspects provides extensive material to help understand drug metabolism within a biological context, and for predicting and mitigating adverse drug reactions.