LC-MS in Drug Bioanalysis

LC-MS in Drug Bioanalysis by Quanyun A Xu, Timothy L Madden

Title: LC-MS in Drug Bioanalysis
Author: Quanyun A Xu, Timothy L Madden
ISBN10: 1461438284
ISBN13: 978-1461438281
Publisher: Not Avail (May 14, 2014)
Language: -
Subcategory: Pharmacology
Size PDF: 1604 kb
Size Fb2: 1702 kb
Rating: 4.7/5
Votes: 402
Pages: 475 pages
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LC-MS in Drug Bioanalysis by Quanyun A Xu, Timothy L Madden


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Clinical pharmacology plays an important role in today’s medicine. Due to the high sensitivity, selectivity, and affordability of a mass spectrometer (MS), the high performance liquid chromatography – mass spectrometry (LC-MS) analytical technique is widely used in the determination of drugs in human biological matrixes for clinical pharmacology. Specifically, LC-MS is used to analyze: anticancer drugs antidementia drugs antidepressant drugs antiepileptic drugs antifundal drug antimicrobial drugs antipsychotic drugs antiretroviral drugs anxiolytic/hypnotic drugs cardiac drugs drugs for addiction immunosuppressant drugs mood stabilizer drugs This book will primarily cover the various methods of validation for LC-MS techniques and applications used in modern clinical pharmacology.